T64R (p.Thr64Arg) variant of IL1R1 (Interleukin-1 receptor type 1)
T64R (p.Thr64Arg) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T64R (p.Thr64Arg) variant details
- p.Thr64Arg
- ExAC rs760945361
- gnomAD rs760945361
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.29
- CADD 14.60
- PolyPhen-2 0.20
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available