T64I (p.Thr64Ile) variant of IL1R1 (Interleukin-1 receptor type 1)
T64I (p.Thr64Ile) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T64I (p.Thr64Ile) variant details
- p.Thr64Ile
- cosmic curated COSV52108
- ExAC rs760945361
- gnomAD rs760945361
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.08
- CADD 9.53
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available