S35C (p.Ser35Cys) variant of IL1R1 (Interleukin-1 receptor type 1)
S35C (p.Ser35Cys) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S35C (p.Ser35Cys) variant details
- p.Ser35Cys
- ExAC rs201587813
- gnomAD rs201587813
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.07
- CADD 20.30
- PolyPhen-2 0.70
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available