S34L (p.Ser34Leu) variant of IL1R1 (Interleukin-1 receptor type 1)
S34L (p.Ser34Leu) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S34L (p.Ser34Leu) variant details
- p.Ser34Leu
- TOPMed rs1374298333
- gnomAD rs1374298333
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.04
- CADD 13.40
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available