S17Y (p.Ser17Tyr) variant of IL1R1 (Interleukin-1 receptor type 1)
S17Y (p.Ser17Tyr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
S17Y (p.Ser17Tyr) variant details
- p.Ser17Tyr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.12
- CADD 15.70
- PolyPhen-2 0.30
- SIFT 0.41
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available