R73T (p.Arg73Thr) variant of IL1R1 (Interleukin-1 receptor type 1)
R73T (p.Arg73Thr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
R73T (p.Arg73Thr) variant details
- p.Arg73Thr
- gnomAD 2-102164930-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.527
- REVEL 0.43
- CADD 24.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available