R26S (p.Arg26Ser) variant of IL1R1 (Interleukin-1 receptor type 1)
R26S (p.Arg26Ser) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
R26S (p.Arg26Ser) variant details
- p.Arg26Ser
- gnomAD 2-102164788-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.05
- CADD 9.58
- PolyPhen-2 0.04
- SIFT 0.39
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available
- Literature evidence available