P85L (p.Pro85Leu) variant of IL1R1 (Interleukin-1 receptor type 1)
P85L (p.Pro85Leu) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
P85L (p.Pro85Leu) variant details
- p.Pro85Leu
- Ensembl rs201278803
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.45
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available