P65S (p.Pro65Ser) variant of IL1R1 (Interleukin-1 receptor type 1)
P65S (p.Pro65Ser) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
P65S (p.Pro65Ser) variant details
- p.Pro65Ser
- gnomAD 2-102164905-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.12
- CADD 7.77
- PolyPhen-2 0.06
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available