P65H (p.Pro65His) variant of IL1R1 (Interleukin-1 receptor type 1)
P65H (p.Pro65His) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P65H (p.Pro65His) variant details
- p.Pro65His
- cosmic curated COSV99292
- TOPMed rs1185879650
- gnomAD rs1185879650
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.12
- CADD 20.30
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available