P45T (p.Pro45Thr) variant of IL1R1 (Interleukin-1 receptor type 1)
P45T (p.Pro45Thr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
P45T (p.Pro45Thr) variant details
- p.Pro45Thr
- gnomAD 2-102164845-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.08
- CADD 7.75
- PolyPhen-2 0.12
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available