P45L (p.Pro45Leu) variant of IL1R1 (Interleukin-1 receptor type 1)
P45L (p.Pro45Leu) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P45L (p.Pro45Leu) variant details
- p.Pro45Leu
- gnomAD 2-102164846-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.09
- CADD 13.60
- PolyPhen-2 0.04
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available