N37K (p.Asn37Lys) variant of IL1R1 (Interleukin-1 receptor type 1)
N37K (p.Asn37Lys) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
N37K (p.Asn37Lys) variant details
- p.Asn37Lys
- gnomAD 2-102164823-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.09
- CADD 16.80
- PolyPhen-2 0.04
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available