L7I (p.Leu7Ile) variant of IL1R1 (Interleukin-1 receptor type 1)
L7I (p.Leu7Ile) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L7I (p.Leu7Ile) variant details
- p.Leu7Ile
- gnomAD 2-102157743-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.12
- CADD 8.76
- PolyPhen-2 0.10
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available