L7F (p.Leu7Phe) variant of IL1R1 (Interleukin-1 receptor type 1)
L7F (p.Leu7Phe) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- 1000Genomes rs200131321
- ExAC rs200131321
- gnomAD rs200131321
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.10
- CADD 10.70
- PolyPhen-2 0.04
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available