L5I (p.Leu5Ile) variant of IL1R1 (Interleukin-1 receptor type 1)
L5I (p.Leu5Ile) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L5I (p.Leu5Ile) variant details
- p.Leu5Ile
- gnomAD 2-102157737-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.09
- CADD 22.80
- PolyPhen-2 0.20
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available