L4F (p.Leu4Phe) variant of IL1R1 (Interleukin-1 receptor type 1)
L4F (p.Leu4Phe) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
L4F (p.Leu4Phe) variant details
- p.Leu4Phe
- gnomAD 2-102157736-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.07
- CADD 16.80
- PolyPhen-2 0.31
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available