L18M (p.Leu18Met) variant of IL1R1 (Interleukin-1 receptor type 1)
L18M (p.Leu18Met) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L18M (p.Leu18Met) variant details
- p.Leu18Met
- gnomAD 2-102157776-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.08
- CADD 22.60
- PolyPhen-2 0.90
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available