L14P (p.Leu14Pro) variant of IL1R1 (Interleukin-1 receptor type 1)
L14P (p.Leu14Pro) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L14P (p.Leu14Pro) variant details
- p.Leu14Pro
- ExAC rs760125077
- gnomAD rs760125077
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.28
- CADD 25.90
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available