L13P (p.Leu13Pro) variant of IL1R1 (Interleukin-1 receptor type 1)
L13P (p.Leu13Pro) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L13P (p.Leu13Pro) variant details
- p.Leu13Pro
- Ensembl rs998308685
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.17
- CADD 17.90
- PolyPhen-2 0.03
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available