K87R (p.Lys87Arg) variant of IL1R1 (Interleukin-1 receptor type 1)
K87R (p.Lys87Arg) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
K87R (p.Lys87Arg) variant details
- p.Lys87Arg
- gnomAD 2-102164972-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.02
- CADD 15.80
- PolyPhen-2 0.06
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available