K80Q (p.Lys80Gln) variant of IL1R1 (Interleukin-1 receptor type 1)
K80Q (p.Lys80Gln) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K80Q (p.Lys80Gln) variant details
- p.Lys80Gln
- ExAC rs778577313
- gnomAD rs778577313
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.05
- CADD 7.72
- PolyPhen-2 0.02
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available