K24T (p.Lys24Thr) variant of IL1R1 (Interleukin-1 receptor type 1)
K24T (p.Lys24Thr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K24T (p.Lys24Thr) variant details
- p.Lys24Thr
- ExAC rs750296992
- gnomAD rs750296992
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.04
- CADD 8.40
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available