I8T (p.Ile8Thr) variant of IL1R1 (Interleukin-1 receptor type 1)
I8T (p.Ile8Thr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I8T (p.Ile8Thr) variant details
- p.Ile8Thr
- ExAC rs761384702
- TOPMed rs761384702
- gnomAD rs761384702
- Missense
- Variant Prioritization Score for Impact Estimate 0.061
- REVEL 0.03
- CADD 6.92
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available