I55M (p.Ile55Met) variant of IL1R1 (Interleukin-1 receptor type 1)
I55M (p.Ile55Met) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
I55M (p.Ile55Met) variant details
- p.Ile55Met
- gnomAD 2-102164877-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.38
- CADD 17.90
- PolyPhen-2 0.89
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available