F83L (p.Phe83Leu) variant of IL1R1 (Interleukin-1 receptor type 1)
F83L (p.Phe83Leu) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
F83L (p.Phe83Leu) variant details
- p.Phe83Leu
- gnomAD 2-102164959-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.41
- CADD 24.70
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available