E25Q (p.Glu25Gln) variant of IL1R1 (Interleukin-1 receptor type 1)
E25Q (p.Glu25Gln) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
E25Q (p.Glu25Gln) variant details
- p.Glu25Gln
- TOPMed rs1205738901
- gnomAD rs1205738901
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.06
- CADD 17.60
- PolyPhen-2 0.83
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available