E25K (p.Glu25Lys) variant of IL1R1 (Interleukin-1 receptor type 1)
E25K (p.Glu25Lys) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
E25K (p.Glu25Lys) variant details
- p.Glu25Lys
- gnomAD 2-102164785-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.12
- CADD 19.30
- PolyPhen-2 0.76
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available