D40G (p.Asp40Gly) variant of IL1R1 (Interleukin-1 receptor type 1)
D40G (p.Asp40Gly) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D40G (p.Asp40Gly) variant details
- p.Asp40Gly
- ExAC rs746323923
- gnomAD rs746323923
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.13
- CADD 10.80
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available