D21Y (p.Asp21Tyr) variant of IL1R1 (Interleukin-1 receptor type 1)
D21Y (p.Asp21Tyr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
D21Y (p.Asp21Tyr) variant details
- p.Asp21Tyr
- gnomAD 2-102157785-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.20
- CADD 35.00
- PolyPhen-2 0.85
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available