D21G (p.Asp21Gly) variant of IL1R1 (Interleukin-1 receptor type 1)
D21G (p.Asp21Gly) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
D21G (p.Asp21Gly) variant details
- p.Asp21Gly
- TOPMed rs1685026814
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.08
- CADD 23.10
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available