A86T (p.Ala86Thr) variant of IL1R1 (Interleukin-1 receptor type 1)
A86T (p.Ala86Thr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
A86T (p.Ala86Thr) variant details
- p.Ala86Thr
- gnomAD 2-102164968-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.34
- CADD 23.00
- PolyPhen-2 0.34
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available