A36T (p.Ala36Thr) variant of IL1R1 (Interleukin-1 receptor type 1)
A36T (p.Ala36Thr) in IL1R1 (Interleukin-1 receptor type 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
A36T (p.Ala36Thr) variant details
- p.Ala36Thr
- gnomAD 2-102164818-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.18
- CADD 21.10
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available