V69M (p.Val69Met) variant of IL1B (Interleukin-1 beta)
V69M (p.Val69Met) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
V69M (p.Val69Met) variant details
- p.Val69Met
- TOPMed rs1438718924
- gnomAD rs1438718924
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.30
- MetaLR 0.24
- MetaSVM -0.77
- CADD 17.40
- PolyPhen-2 0.62
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available