V69A (p.Val69Ala) variant of IL1B (Interleukin-1 beta)
V69A (p.Val69Ala) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
V69A (p.Val69Ala) variant details
- p.Val69Ala
- gnomAD 2-112833469-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.29
- MetaLR 0.27
- MetaSVM -0.67
- CADD 20.70
- PolyPhen-2 0.74
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available