V68A (p.Val68Ala) variant of IL1B (Interleukin-1 beta)
V68A (p.Val68Ala) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
V68A (p.Val68Ala) variant details
- p.Val68Ala
- TOPMed rs1275442201
- gnomAD rs1275442201
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.35
- MetaLR 0.28
- MetaSVM -0.70
- CADD 22.70
- PolyPhen-2 0.81
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available