T92I (p.Thr92Ile) variant of IL1B (Interleukin-1 beta)
T92I (p.Thr92Ile) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T92I (p.Thr92Ile) variant details
- p.Thr92Ile
- 1000Genomes rs200401035
- ExAC rs200401035
- TOPMed rs200401035
- gnomAD rs200401035
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.12
- MetaLR 0.14
- MetaSVM -0.97
- CADD 15.80
- PolyPhen-2 0.76
- SIFT 0.09
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available