T84I (p.Thr84Ile) variant of IL1B (Interleukin-1 beta)
T84I (p.Thr84Ile) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T84I (p.Thr84Ile) variant details
- p.Thr84Ile
- TOPMed rs1211756181
- Missense
- Variant Prioritization Score for Impact Estimate 0.0849
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.06
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available