S35A (p.Ser35Ala) variant of IL1B (Interleukin-1 beta)
S35A (p.Ser35Ala) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S35A (p.Ser35Ala) variant details
- p.Ser35Ala
- ExAC rs755758115
- gnomAD rs755758115
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.09
- MetaLR 0.10
- MetaSVM -1.07
- CADD 2.13
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available