S16G (p.Ser16Gly) variant of IL1B (Interleukin-1 beta)
S16G (p.Ser16Gly) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S16G (p.Ser16Gly) variant details
- p.Ser16Gly
- TOPMed rs1682086803
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.20
- MetaLR 0.19
- MetaSVM -0.74
- CADD 25.10
- PolyPhen-2 0.21
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available