R75K (p.Arg75Lys) variant of IL1B (Interleukin-1 beta)
R75K (p.Arg75Lys) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
R75K (p.Arg75Lys) variant details
- p.Arg75Lys
- Ensembl rs1682028552
- Missense
- Variant Prioritization Score for Impact Estimate 0.0789
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -0.98
- CADD 0.04
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available