R75* (p.Arg75Ter) variant of IL1B (Interleukin-1 beta)
R75* (p.Arg75Ter) in IL1B (Interleukin-1 beta) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
R75* (p.Arg75Ter) variant details
- p.Arg75Ter
- gnomAD 2-112833453-C-CAG
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.422
- CADD 23.70
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available