R62G (p.Arg62Gly) variant of IL1B (Interleukin-1 beta)
R62G (p.Arg62Gly) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
R62G (p.Arg62Gly) variant details
- p.Arg62Gly
- gnomAD 2-112833491-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.21
- MetaLR 0.21
- MetaSVM -0.84
- CADD 16.30
- PolyPhen-2 0.62
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available