R51* (p.Arg51Ter) variant of IL1B (Interleukin-1 beta)
R51* (p.Arg51Ter) in IL1B (Interleukin-1 beta) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R51* (p.Arg51Ter) variant details
- p.Arg51Ter
- rs1466522013
- NCI-TCGA Cosmic COSV5452
- gnomAD rs1466522013
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.402
- CADD 33.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available