Q63R (p.Gln63Arg) variant of IL1B (Interleukin-1 beta)
Q63R (p.Gln63Arg) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
Q63R (p.Gln63Arg) variant details
- p.Gln63Arg
- 1000Genomes rs200278471
- ExAC rs200278471
- TOPMed rs200278471
- gnomAD rs200278471
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.11
- MetaLR 0.08
- MetaSVM -1.00
- CADD 5.10
- PolyPhen-2 0.02
- SIFT 0.55
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available