Q31H (p.Gln31His) variant of IL1B (Interleukin-1 beta)
Q31H (p.Gln31His) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Q31H (p.Gln31His) variant details
- p.Gln31His
- gnomAD 2-112835572-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.14
- MetaLR 0.16
- MetaSVM -0.94
- CADD 19.50
- PolyPhen-2 0.89
- SIFT 0.12
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available