P80A (p.Pro80Ala) variant of IL1B (Interleukin-1 beta)
P80A (p.Pro80Ala) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
P80A (p.Pro80Ala) variant details
- p.Pro80Ala
- gnomAD 2-112833437-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -0.99
- CADD 0.35
- PolyPhen-2 0.01
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available