P5T (p.Pro5Thr) variant of IL1B (Interleukin-1 beta)
P5T (p.Pro5Thr) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
P5T (p.Pro5Thr) variant details
- p.Pro5Thr
- ESP rs370988408
- ExAC rs370988408
- TOPMed rs370988408
- gnomAD rs370988408
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.60
- MetaLR 0.69
- MetaSVM 0.66
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the HGDP:PALESTINIAN population (allele frequency 0.013)
- Structural context available