P43S (p.Pro43Ser) variant of IL1B (Interleukin-1 beta)
P43S (p.Pro43Ser) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P43S (p.Pro43Ser) variant details
- p.Pro43Ser
- gnomAD rs1425569299
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.09
- MetaLR 0.03
- MetaSVM -0.99
- CADD 5.12
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available