M77V (p.Met77Val) variant of IL1B (Interleukin-1 beta)
M77V (p.Met77Val) in IL1B (Interleukin-1 beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
M77V (p.Met77Val) variant details
- p.Met77Val
- TOPMed rs1682028333
- Missense
- Variant Prioritization Score for Impact Estimate 0.0838
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.08
- CADD 0.64
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available